Description

p-Toluenesulfonyl-L-Arginine Methyl Ester Hcl CAS NO 901-47-3 is a protected derivative of the amino acid L-arginine, widely used as a key synthetic intermediate and biochemical reagent. Its primary value lies in providing a stable, activated form of arginine for controlled peptide synthesis and enzymatic studies. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity building blocks for drug discovery and biochemical applications.

Application

• Peptide Synthesis: Serves as a crucial protected arginine precursor in solid-phase and solution-phase peptide synthesis for research and pharmaceutical development.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study protease and trypsin-like enzyme activity and mechanisms.
• Pharmaceutical Intermediates: Acts as a key building block in the synthesis of more complex active pharmaceutical ingredients (APIs) and drug candidates.
• Proteomics & Diagnostics: Employed in the development of diagnostic kits and proteomic research tools that target arginine-specific processes.
• Academic & Industrial R&D: A fundamental reagent for universities and contract research organizations (CROs) conducting cutting-edge research in biochemistry and medicinal chemistry.

Basic Information

Product Name	p-Toluenesulfonyl-L-Arginine Methyl Ester Hcl
CAS No.	901-47-3
Molecular Formula	C14H23ClN4O4S
Molecular Weight	378.87 g/mol
Synonyms	Tosyl-L-arginine methyl ester hydrochloride; TAME hydrochloride; Nα-Tosyl-L-arginine methyl ester hydrochloride; L-Arginine, N2-(4-methylphenyl)sulfonyl-, methyl ester, hydrochloride; Methyl Nα-tosyl-L-argininate hydrochloride; TAME HCl; 901-47-3; p-Tosyl-L-arginine methyl ester HCl
EINECS	Contact for details

Quality Control

Our p-Toluenesulfonyl-L-Arginine Methyl Ester Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Ensure proper ventilation in the storage area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.