Description

3-Trifluoromethylphenol is a versatile fluorinated aromatic compound, also known by its CAS number 98-17-9. This specialty chemical is valued for its unique trifluoromethyl (-CF3) group, which imparts enhanced lipophilicity, metabolic stability, and electron-withdrawing properties to molecular structures. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediates: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the -CF3 group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a core component in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials for electronic displays.
• Polymer & Resin Modifiers: Incorporated to modify the properties of specialty polymers, enhancing chemical resistance, thermal stability, and surface characteristics.
• Dye & Pigment Manufacturing: Serves as a precursor for high-performance, light-fast fluorinated dyes and pigments.
• Chemical Research & Development: A valuable reagent in organic synthesis for introducing the trifluoromethylphenol moiety into complex molecules.

Basic Information

Product Name	3-Trifluoromethylphenol
CAS No.	98-17-9
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	m-Trifluoromethylphenol; 3-Hydroxybenzotrifluoride; α,α,α-Trifluoro-m-cresol; 3-(Trifluoromethyl)phenol; m-Hydroxybenzotrifluoride; 1-Hydroxy-3-(trifluoromethyl)benzene; NSC 2217; Benzene, 1-hydroxy-3-(trifluoromethyl)-
EINECS	202-642-9

Quality Control

Our 3-Trifluoromethylphenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (IR, NMR), to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	70 - 74 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.