Description

Chlorzoxazone CAS NO 95-25-0 is a centrally acting skeletal muscle relaxant belonging to the benzoxazolone class. It is a key pharmaceutical active ingredient (API) valued for its efficacy in relieving discomfort associated with acute, painful musculoskeletal conditions. This compound is essential for manufacturers in the pharmaceutical industry, particularly those producing prescription medications for muscle spasms and related disorders. Consistent quality and reliable supply are critical for ensuring the safety and effectiveness of the final drug product.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription muscle relaxant medications.
• Tablet Formulation: Incorporated into solid oral dosage forms for the treatment of muscle spasms and pain.
• Generic Drug Manufacturing: Serves as a critical component for producing bioequivalent generic versions of branded muscle relaxants.
• Clinical Research: Used in preclinical and clinical studies for developing new musculoskeletal therapies.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Bulk Pharmaceutical Intermediates: May be used in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Chlorzoxazone
CAS No.	95-25-0
Molecular Formula	C7H4ClNO2
Molecular Weight	169.56 g/mol
Synonyms	5-Chloro-2-benzoxazolinone; 5-Chloro-2(3H)-benzoxazolone; Paraflex; Solaxin; Muscol; Chlorzoxazon; 5-Chlorobenzoxazolin-2-one; 2-Benzoxazolinone, 5-chloro-
EINECS	202-400-2

Quality Control

Our Chlorzoxazone is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical use. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, typically referencing USP or EP monographs. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.