Description

2-Chloro-n-(3-Fluorophenyl)Pyrimidin-4-Amine CAS NO 898805-58-8 is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific pyrimidine derivatives.

Basic Information

Item	Details
Product Name	2-Chloro-n-(3-Fluorophenyl)Pyrimidin-4-Amine
CAS No.	898805-58-8
Molecular Formula	C10H7ClFN3
Molecular Weight	223.63 g/mol
Synonyms	4-Amino-2-chloro-N-(3-fluorophenyl)pyrimidine; 2-Chloro-N-(3-fluorophenyl)-4-pyrimidinamine; 2-Chloro-N-(3-fluorophenyl)pyrimidin-4-amine; N-(3-Fluorophenyl)-2-chloropyrimidin-4-amine; 898805-58-8; 2-Chloro-4-amino-N-(3-fluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(3-Fluorophenyl)Pyrimidin-4-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for verification. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.