Description

6-(2-Fluorophenyl)-3-Pyridinecarbaldehyde is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated aromatic motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the fluorophenyl-pyridine scaffold can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where fluorine substitution tunes electronic properties.
• Chemical Biology Probes: Utilized in the design of fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	6-(2-Fluorophenyl)-3-Pyridinecarbaldehyde
CAS No.	898795-78-3
Molecular Formula	C12H8FNO
Molecular Weight	201.20 g/mol
Synonyms	3-Formyl-6-(2-fluorophenyl)pyridine; 2-Fluoro-6-pyridin-3-ylbenzaldehyde; 6-(2-Fluorophenyl)nicotinaldehyde; 3-Pyridinecarboxaldehyde, 6-(2-fluorophenyl)-; 2-Fluorophenyl-3-pyridyl ketone (related); 6-(o-Fluorophenyl)-3-pyridinecarboxaldehyde; 898795-78-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 6-(2-Fluorophenyl)-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.