Description

2',5'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is a specialized fluorinated organic building block featuring a protected carbonyl group, making it a valuable intermediate in advanced synthetic chemistry. Its molecular architecture is engineered to facilitate the controlled introduction of complex functionalities, offering researchers and process chemists a high-purity starting material for demanding applications. This compound is primarily utilized in the research and development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where precise fluorination and functional group manipulation are critical.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring specific fluorination patterns for enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms and the protected ketone moiety can contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D laboratories for constructing complex molecular scaffolds, leveraging its reactive sites for further chemical transformations.
• Fluorine Chemistry Studies: Acts as a model compound for investigating new fluorination methodologies or the behavior of fluorinated intermediates in synthetic pathways.

Basic Information

Product Name	2',5'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone
CAS No.	898786-90-8
Molecular Formula	C₁₇H₂₂F₂O₃
Molecular Weight	312.36 g/mol
Synonyms	5-(5,5-Dimethyl-1,3-dioxan-2-yl)-2',5'-difluorovalerophenone; 1-[2,5-Difluorophenyl]-5-(5,5-dimethyl-1,3-dioxan-2-yl)pentan-1-one; 2',5'-Difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)-1-phenylpentan-1-one; Valerophenone, 2',5'-difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)-; Difluorophenyl protected ketone intermediate
EINECS	Contact for details

Quality Control

Every batch of 2',5'-Difluoro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles via techniques such as HPLC, GC, NMR, and mass spectrometry is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.