Description

n-(5-Ethyl-1,3,4-Thiadiazol-2-Yl)-1-(4-Fluorophenyl)-4-Oxo-1,4-Dihydro-3-Pyridazinecarboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of investigational new drugs, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the multi-step synthesis of complex target molecules for pre-clinical and clinical development phases.
• Biochemical Tool Compound: May be utilized in vitro to study biological mechanisms and validate novel therapeutic targets.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized, high-value organic compounds.

Basic Information

Product Name	n-(5-Ethyl-1,3,4-Thiadiazol-2-Yl)-1-(4-Fluorophenyl)-4-Oxo-1,4-Dihydro-3-Pyridazinecarboxamide
CAS No.	898490-09-0
Molecular Formula	C₁₆H₁₄FN₅O₂S
Molecular Weight	359.38 g/mol
Synonyms	1-(4-Fluorophenyl)-4-oxo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-1,4-dihydropyridazine-3-carboxamide; 898490-09-0; 5-Ethyl-1,3,4-thiadiazol-2-amine derivative; Pyridazinecarboxamide, N-(5-ethyl-1,3,4-thiadiazol-2-yl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydro-; Fluorophenyl thiadiazolyl pyridazinecarboxamide
EINECS	Contact for details

Quality Control

Our production of n-(5-Ethyl-1,3,4-Thiadiazol-2-Yl)-1-(4-Fluorophenyl)-4-Oxo-1,4-Dihydro-3-Pyridazinecarboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.