Description

3-Pyrimidin-2-Ylbenzyl Chloride is a versatile and high-value organic building block, specifically a benzyl chloride derivative functionalized with a pyrimidine ring. This compound is critical for its role as a key intermediate in modern synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine moiety.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Pyrimidin-2-Ylbenzyl Chloride
CAS No.	898289-51-5
Molecular Formula	C11H9ClN2
Molecular Weight	204.66 g/mol
Synonyms	(3-Pyrimidin-2-ylphenyl)methyl chloride; 2-[(3-Chloromethyl)phenyl]pyrimidine; 1-(Chloromethyl)-3-(pyrimidin-2-yl)benzene; 3-(Pyrimidin-2-yl)benzyl chloride; 2-(3-Chloromethylphenyl)pyrimidine; α-Chloro-3-(2-pyrimidinyl)toluene
EINECS	Contact for details

Quality Control

Our 3-Pyrimidin-2-Ylbenzyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.