Description

4-Chloro-5-Fluoro-6-Methylpyrimidine is a high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical sectors. It is primarily needed by R&D chemists and process development scientists working on fluorinated heterocycles, nucleoside analogs, and targeted small molecule libraries.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Building block for developing new herbicides and fungicides with enhanced activity and selectivity.
• Material Science: Precursor for functionalized pyrimidine derivatives used in organic electronic materials.
• Chemical Biology: Useful for creating molecular probes and labeled compounds due to its reactive chloro and fluoro substituents.
• Custom Synthesis: Serves as a versatile starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	4-Chloro-5-Fluoro-6-Methylpyrimidine
CAS No.	898044-55-8
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	4-Chloro-5-fluoro-6-methylpyrimidine; 6-Methyl-4-chloro-5-fluoropyrimidine; 5-Fluoro-4-chloro-6-methylpyrimidine; Pyrimidine, 4-chloro-5-fluoro-6-methyl-; 898044-55-8; 4-Chloro-5-fluoro-6-methyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-6-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.