Description

4-Chloro-5-Fluoro-2-Methyl-Pyrimidine is a high-value halogenated pyrimidine building block, essential for advanced organic synthesis. Its precise molecular structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the development of specialty polymers and functional materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	4-Chloro-5-Fluoro-2-Methyl-Pyrimidine
CAS No.	898044-50-3
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	2-Methyl-4-chloro-5-fluoropyrimidine; 5-Fluoro-4-chloro-2-methylpyrimidine; 4-Chloro-5-fluoro-2-methyl-1,3-diazine; 898044-50-3; Pyrimidine, 4-chloro-5-fluoro-2-methyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-2-Methyl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.