Description

4-Chloroquinazoline-2-Carbonitrile is a versatile and high-value heterocyclic building block, primarily used in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the chloroquinazoline scaffold and the nitrile group serve as key handles for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and photoactive materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	4-Chloroquinazoline-2-Carbonitrile
CAS No.	898044-49-0
Molecular Formula	C9H4ClN3
Molecular Weight	189.60 g/mol
Synonyms	2-Cyano-4-chloroquinazoline; 4-Chloro-2-cyanoquinazoline; 4-Chloroquinazoline-2-carbonitrile; Quinazoline-2-carbonitrile, 4-chloro-; 898044-49-0
EINECS	Contact for details

Quality Control

Our 4-Chloroquinazoline-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.