Description

4-Fluoro-3-Iodophenol is a versatile halogenated phenol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity offered by the combination of fluorine and iodine substituents on the phenolic ring, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated and iodinated aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl structures.
• Polymer Modification: Employed to introduce halogenated phenolic units into polymer chains, altering thermal stability, flame retardancy, and solubility properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Fluoro-3-Iodophenol
CAS No.	897956-98-8
Molecular Formula	C6H4FIO
Molecular Weight	237.99 g/mol
Synonyms	3-Iodo-4-fluorophenol; 4-Fluoro-3-iodo-1-hydroxybenzene; 1-Hydroxy-3-iodo-4-fluorobenzene; Phenol, 4-fluoro-3-iodo-; 4-Fluoro-3-iodophenol; 3-Iodo-4-fluorophenol; 4-Fluoro-3-iodo-phenol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Iodophenol is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.