Description

n-Cyclohexyl-1-Methyl-6-(4-Methylpiperazin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of targeted kinase inhibitors and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel kinase inhibitors targeting various disease pathways.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in oncology and immunology research.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological mechanisms and validate drug targets.
• Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.
• Custom Synthesis: Available for contract manufacturing and custom synthesis projects requiring complex heterocyclic scaffolds.

Basic Information

Product Name	n-Cyclohexyl-1-Methyl-6-(4-Methylpiperazin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	897758-08-6
Molecular Formula	C₁₇H₂₇N₇
Molecular Weight	329.45 g/mol
Synonyms	4-Amino-1-methyl-6-(4-methyl-1-piperazinyl)-N-cyclohexyl-1H-pyrazolo[3,4-d]pyrimidine; 1-Methyl-6-(4-methylpiperazin-1-yl)-N-cyclohexyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 897758-08-6; Pyrazolopyrimidine derivative; Kinase inhibitor intermediate; CAS 897758-08-6
EINECS	Contact for details

Quality Control

Our production of n-Cyclohexyl-1-Methyl-6-(4-Methylpiperazin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that implement cGMP principles where applicable. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.