Description

Ethyl 5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its complex pyrazolopyrimidine core, featuring a trifluoromethyl group, is engineered to impart significant biological activity and metabolic stability in drug candidates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors seeking to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing novel fungicides and herbicides, leveraging the bioactivity of the pyrazolopyrimidine scaffold.
• Chemical Biology: Serves as a versatile probe or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic systems for material science and specialty chemical applications.

Basic Information

Product Name	Ethyl 5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	897544-32-0
Molecular Formula	C₁₇H₁₆F₃N₅O₂
Molecular Weight	379.34 g/mol
Synonyms	Ethyl 5-(1,3-dimethylpyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 897544-32-0; 5-(1,3-Dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)-, ethyl ester; Ethyl 5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (tautomer); SCHEMBL21824027; AKOS040759232; BDBM50389339
EINECS	Contact for details

Quality Control

Our Ethyl 5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.