Description

7-Chloropyrido[3,2-D]Pyrimidin-4(3H)-One is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its role as a key precursor in the development of novel kinase inhibitors and other biologically active molecules, enabling critical structure-activity relationship (SAR) studies. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting oncology, inflammatory diseases, and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A crucial synthetic precursor for the development of novel small-molecule drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study specific biological pathways and target validation.
• Contract Research & Development (CRO): Supplied to CROs and discovery service providers for client-directed synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and bioorganic synthesis.
• Custom Synthesis: The starting point for the custom manufacture of more complex, proprietary compounds under confidentiality agreements.

Basic Information

Product Name	7-Chloropyrido[3,2-D]Pyrimidin-4(3H)-One
CAS No.	897360-16-6
Molecular Formula	C7H4ClN3O
Molecular Weight	181.58 g/mol
Synonyms	7-Chloro-3H-pyrido[3,2-d]pyrimidin-4-one; 7-Chloro-4-hydroxy-pyrido[3,2-d]pyrimidine; 7-Chloro-4(3H)-pyrido[3,2-d]pyrimidinone; 4(3H)-Pyrido[3,2-d]pyrimidinone, 7-chloro-; 897360-16-6; 7-Chloro-4-hydroxypyrido[3,2-d]pyrimidine; 7-Chloro-4-oxo-3,4-dihydropyrido[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Chloropyrido[3,2-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry characterization. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.