Description

5-Chloropyrimidine-2-Carboxylic Acid Methyl Ester is a high-purity, versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive chloropyrimidine core and ester functionality, enabling precise molecular construction. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for the creation of specialized polymers, ligands for catalysis, or organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules on a commercial scale.

Basic Information

Product Name	5-Chloropyrimidine-2-Carboxylic Acid Methyl Ester
CAS No.	894797-00-3
Molecular Formula	C7H5ClN2O2
Molecular Weight	184.58 g/mol
Synonyms	Methyl 5-chloropyrimidine-2-carboxylate; 2-Pyrimidinecarboxylic acid, 5-chloro-, methyl ester; 5-Chloro-2-pyrimidinecarboxylic acid methyl ester; Methyl 5-chloro-2-pyrimidinecarboxylate; 5-Chloro-2-(methoxycarbonyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloropyrimidine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.