Description

2-Cyano-5-Fluorobenzaldehyde is a high-value fluorinated aromatic aldehyde building block, distinguished by its reactive aldehyde and cyano functional groups. This compound is critical for the synthesis of complex molecules, offering chemists a versatile handle for constructing heterocycles and advanced intermediates. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated benzimidazole or quinazoline cores.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as non-linear optical (NLO) chromophores and organic light-emitting diodes (OLEDs).
• Fluorescent Probe Synthesis: Utilized to build fluorogenic dyes and molecular probes for bioimaging and diagnostic applications.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs engaged in custom synthesis and scale-up projects.

Basic Information

Product Name	2-Cyano-5-Fluorobenzaldehyde
CAS No.	894779-76-1
Molecular Formula	C8H4FNO
Molecular Weight	149.12 g/mol
Synonyms	5-Fluoro-2-formylbenzonitrile; 5-Fluorophthalaldehyde-2-nitrile; 2-Formyl-5-fluorobenzonitrile; 5-Fluoro-2-cyanobenzaldehyde; Benzonitrile, 5-fluoro-2-formyl-; 5-Fluoroisophthalaldehyde mononitrile
EINECS	Contact for details

Quality Control

Our 2-Cyano-5-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.