Description

Prepro-Neuromedin S (70-103) (Human) is a specific bioactive peptide fragment derived from the human neuromedin S precursor protein. This compound is of significant value for advanced research in neuroendocrinology and metabolic regulation, serving as a critical tool for studying receptor binding and signal transduction pathways. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on peptide-based drug discovery and metabolic disease research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the physiological roles of neuromedin S, including its effects on circadian rhythms, appetite regulation, and energy homeostasis.
• Receptor-Ligand Interaction Studies: Essential for in vitro binding assays to characterize and quantify interactions with the neuromedin S receptor (NMU2R).
• Drug Discovery & Development: Serves as a lead compound or molecular template for the design and screening of novel peptide therapeutics targeting metabolic and neurological disorders.
• Cell Signaling Pathway Analysis: Applied in cell-based assays to elucidate downstream signaling cascades and cellular responses activated by neuromedin S fragments.
• Antibody Production & Immunoassay Development: Utilized as an immunogen for generating specific antibodies or as a calibrator in ELISA and other immunoassay formats.
• Academic & Clinical Research: Supports fundamental research into the connection between neuropeptides, stress response, and metabolic syndrome.

Basic Information

Product Name	Prepro-Neuromedin S (70-103) (Human)
CAS No.	894454-10-5
Molecular Formula	C164H262N50O48S2
Molecular Weight	3799.3 g/mol
Synonyms	Neuromedin S (70-103); hNmS(70-103); Prepro-NmS (70-103); NmS-34; Human Neuromedin S Precursor Fragment; Neuromedin S Long Fragment; TFA salt of Neuromedin S (70-103); CAS 894454-10-5
EINECS	Contact for details

Quality Control

Our Prepro-Neuromedin S (70-103) (Human) is manufactured under strict quality systems suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This hygroscopic and easily oxidized peptide should be handled under an inert atmosphere when possible and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Sequence	H-Asn-Leu-Ser-Leu-Gly-Leu-Ala-Arg-Lys-Tyr-Leu-Glu-Leu-Gln-Arg-Ala-Arg-Asn-Arg-Asn-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 (Disulfide bridge: Cys2-Cys7)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.