Description

3-Fluoro-2'-Methyl[1,1'-Biphenyl]-4-Amine is a high-purity biphenyl derivative featuring a strategically placed fluorine atom and an amine functional group. This compound matters as a versatile and valuable pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for more complex heterocyclic systems in medicinal chemistry.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Fluoro-2'-Methyl[1,1'-Biphenyl]-4-Amine
CAS No.	893735-65-4
Molecular Formula	C₁₃H₁₂FN
Molecular Weight	201.24 g/mol
Synonyms	[1,1'-Biphenyl]-4-amine, 3-fluoro-2'-methyl-; 3-Fluoro-2'-methylbiphenyl-4-amine; 4-Amino-3-fluoro-2'-methylbiphenyl; 2'-Methyl-3-fluorobiphenyl-4-amine; 3-Fluoro-2'-methyl-4-aminobiphenyl; 3-Fluoro-2'-methyl-[1,1'-biphenyl]-4-amine; 4-Amino-3'-fluoro-2-methylbiphenyl (isomer); 893735-65-4
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2'-Methyl[1,1'-Biphenyl]-4-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory support documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.