Description

1-(4-Fluorobenzyl)-2,5-Dioxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2',3'-D]Pyrimidine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Biochemical Tool Compound: Serves as a research chemical for probing biological mechanisms and enzyme inhibition studies in academic and industrial settings.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for specialized applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	1-(4-Fluorobenzyl)-2,5-Dioxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2',3'-D]Pyrimidine-3-Carbonitrile
CAS No.	893700-42-0
Molecular Formula	C20H11FN4O2
Molecular Weight	358.33 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-2,5-dioxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carbonitrile; Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carbonitrile, 1-[(4-fluorophenyl)methyl]-1,5-dihydro-2,5-dioxo-; CAS 893700-42-0; 1-(4-Fluorobenzyl)-2,5-dioxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carbonitrile; 1-(4-Fluorobenzyl)dipyrido[1,2-a:2',3'-d]pyrimidine-2,5(1H,3H)-dione-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-2,5-Dioxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2',3'-D]Pyrimidine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.