Description

C-(2'-Fluoro-Biphenyl-4-Yl)-Methylamine Hydrochloride CAS NO 893649-05-3 is a high-purity, fluorinated biphenyl derivative supplied as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides and herbicides, leveraging the stability of the biphenyl core and fluorine substitution.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or complex organic catalysts in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its rigid biphenyl structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Custom Synthesis and Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to advanced R&D needs.

Basic Information

Product Name	C-(2'-Fluoro-Biphenyl-4-Yl)-Methylamine Hydrochloride
CAS No.	893649-05-3
Molecular Formula	C₁₄H₁₃ClFN
Molecular Weight	249.71 g/mol
Synonyms	1-[(2'-Fluoro[1,1'-biphenyl]-4-yl)methyl]methanamine hydrochloride; (2'-Fluorobiphenyl-4-yl)methylamine hydrochloride; 4-(Aminomethyl)-2'-fluorobiphenyl hydrochloride; 2'-Fluoro-4-(aminomethyl)biphenyl hydrochloride; 1-(2'-Fluorobiphenyl-4-yl)methanamine hydrochloride; α-Amino-2'-fluoro-4-biphenylmethane hydrochloride; [1,1'-Biphenyl]-4-methanamine, 2'-fluoro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our C-(2'-Fluoro-Biphenyl-4-Yl)-Methylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.