Description

4-Chloro-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, heterocyclic organic compound belonging to the pyridopyrimidinone class. This advanced pharmaceutical intermediate is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

This compound serves as a versatile and critical intermediate in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the research and development of kinase inhibitors for oncology and inflammatory diseases.
• Chemical Synthesis Building Block: Used in the construction of complex fused heterocyclic systems for medicinal chemistry programs.
• Biochemical Research: Employed in the study of enzyme-substrate interactions and structure-activity relationship (SAR) modeling.
• Agrochemical Research: Investigated as a potential intermediate for novel crop protection agents.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.

Basic Information

Product Name	4-Chloro-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	893444-36-5
Molecular Formula	C7H6ClN3O
Molecular Weight	183.59 g/mol
Synonyms	4-Chloro-5,6-dihydro-8H-pyrido[2,3-d]pyrimidin-7-one; 4-Chloro-7,8-dihydro-5H-pyrido[2,3-d]pyrimidin-7-one; 4-Chloro-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one; 893444-36-5; 4-Chloro-8H-pyrido[2,3-d]pyrimidin-7-one, 5,6-dihydro-; 4-Chloro-5,6-dihydro-8H-pyrido[2,3-d]pyrimidin-7-one; 4-Chloro-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications from research to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.