Description

4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-Piperazinyl)Ethoxy]-5-[(Tetrahydro-2H-Pyran-4-Yl)Oxy]- is a sophisticated heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical pharmacological intermediate, particularly valued for its potential in modulating specific biological pathways. It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery and synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various disease states.
• Kinase Inhibitor Research: Used in the development and screening of compounds designed to inhibit specific kinase enzymes involved in cell signaling.
• Oncology Research: Investigated as a core structure for novel anti-cancer agents due to its quinazolinone scaffold.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological processes and validate drug targets.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-Piperazinyl)Ethoxy]-5-[(Tetrahydro-2H-Pyran-4-Yl)Oxy]-
CAS No.	893428-67-6
Molecular Formula	C20H28N4O4
Molecular Weight	388.46 g/mol
Synonyms	7-[2-(4-Methylpiperazin-1-yl)ethoxy]-5-[(oxan-4-yl)oxy]quinazolin-4(3H)-one; 5-(Tetrahydro-2H-pyran-4-yloxy)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-4(3H)-quinazolinone; UNII-9F8T171N8P; 9F8T171N8P; BDBM50111257; AKOS025310994; ZINC000003869007; AOB67717
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and LC-MS to ensure structural identity and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP-compliant practices ensures consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.