Description

3-(3-Methoxybenzyl)-2-Thioxo-2,3-Dihydro[1]Benzofuro[3,2-D]Pyrimidin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the benzofuropyrimidinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs, especially within oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D labs.
• API Synthesis: Serves as a core scaffold for constructing final active pharmaceutical ingredients, requiring stringent purity and consistency.
• Biochemical Research: Employed as a reference standard or inhibitor in biochemical assays to study enzyme kinetics and mechanisms of action.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	3-(3-Methoxybenzyl)-2-Thioxo-2,3-Dihydro[1]Benzofuro[3,2-D]Pyrimidin-4(1H)-One
CAS No.	892300-30-0
Molecular Formula	C20H14N2O3S
Molecular Weight	362.40 g/mol
Synonyms	3-(3-Methoxybenzyl)-2-thioxo-1,2-dihydrobenzofuro[3,2-d]pyrimidin-4(3H)-one; 1H-Benzofuro[3,2-d]pyrimidin-4(3H)-one, 3-[(3-methoxyphenyl)methyl]-2-thioxo-2,3-dihydro-; 892300-30-0; Benzofuro[3,2-d]pyrimidinone derivative; 3-(3-Methoxybenzyl)-2-mercaptobenzofuro[3,2-d]pyrimidin-4(3H)-one (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Methoxybenzyl)-2-Thioxo-2,3-Dihydro[1]Benzofuro[3,2-D]Pyrimidin-4(1H)-One is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this light-sensitive compound.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.