Description

tert-Butyl 3-(7-Hydroxypyrazolo[1,5-A]Pyrimidin-5-Yl)Piperidine-1-Carboxylate is a high-purity pharmaceutical intermediate and building block of significant interest in modern drug discovery. Its value lies in its complex heterocyclic structure, which serves as a key scaffold for synthesizing novel bioactive molecules targeting a range of therapeutic areas. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for clinical research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing novel small-molecule kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries via parallel and combinatorial synthesis.
• Oncology Drug Candidates: Integral to the research and development pathway for potential anti-cancer therapeutics.
• CNS-Targeted Compounds: Employed in the synthesis of molecules designed to cross the blood-brain barrier for neurological applications.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 3-(7-Hydroxypyrazolo[1,5-A]Pyrimidin-5-Yl)Piperidine-1-Carboxylate
CAS No.	891494-66-9
Molecular Formula	C16H22N4O3
Molecular Weight	318.37 g/mol
Synonyms	1-Boc-3-(7-hydroxypyrazolo[1,5-a]pyrimidin-5-yl)piperidine; tert-Butyl 3-(7-hydroxypyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate; 5-(1-Boc-3-piperidinyl)-7-hydroxypyrazolo[1,5-a]pyrimidine; 7-Hydroxy-5-(1-Boc-piperidin-3-yl)pyrazolo[1,5-a]pyrimidine; 3-(7-Hydroxypyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylic acid tert-butyl ester; BOC-3-(7-Hydroxy-pyrazolo[1,5-a]pyrimidin-5-yl)-piperidine; 891494-66-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(7-Hydroxypyrazolo[1,5-A]Pyrimidin-5-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.