Description

1,2,3,4-Tetrahydro-6-Methyl-4-(4-Bromophenyl)-2-Oxo-5-Pyrimidinecarboxylic Acid is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals. Pharmaceutical research and development teams, as well as custom synthesis laboratories, need this high-purity intermediate to create new therapeutic agents and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for biological activity.
• Material Science: Serves as a precursor for advanced organic materials, including ligands for catalysis and components for organic electronics.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploration of new chemical spaces.
• Custom Synthesis: A starting material for the tailored production of complex, brominated pyrimidine derivatives for specific client projects.
• Chemical Biology: Useful as a probe or scaffold in the study of enzyme inhibition and other biochemical interactions.

Basic Information

Product Name	1,2,3,4-Tetrahydro-6-Methyl-4-(4-Bromophenyl)-2-Oxo-5-Pyrimidinecarboxylic Acid
CAS No.	891190-54-8
Molecular Formula	C12H11BrN2O3
Molecular Weight	311.13 g/mol
Synonyms	4-(4-Bromophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid; 4-(4-Bromophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-4-(4-bromophenyl)-2-oxo-; Tetrahydro-6-methyl-4-(4-bromophenyl)-2-oxo-5-pyrimidinecarboxylic acid; CAS 891190-54-8
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-6-Methyl-4-(4-Bromophenyl)-2-Oxo-5-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with full batch traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.