Description

3-Cyclopropyl-4-Fluoroaniline is a high-purity, advanced pharmaceutical intermediate (API) characterized by its unique cyclopropyl and fluoro-substituted aniline structure. This compound is critical for medicinal chemists in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the bioactivity of the cyclopropyl and fluorine groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific electronic or optical properties.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and fluorescent tags used in biochemical and diagnostic research.

Basic Information

Product Name	3-Cyclopropyl-4-Fluoroaniline
CAS No.	890129-90-5
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	4-Fluoro-3-cyclopropylaniline; 3-Cyclopropyl-4-fluoro-benzenamine; Benzenamine, 3-cyclopropyl-4-fluoro-; 1-Cyclopropyl-2-fluoro-4-aminobenzene; 3-Cyclopropyl-4-fluoro-phenylamine; 4-Amino-2-fluoro-1-cyclopropylbenzene; 3-Cyclopropyl-4-fluoroaniline (primary synonym)
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-4-Fluoroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.