Description

7-Amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile is a high-value, multi-functional heterocyclic building block. This compound matters for its unique trifluoromethylated triazolopyrimidine core, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the design and synthesis of advanced pesticides and herbicides, leveraging the bioactivity of the triazolopyrimidine scaffold.
• Chemical Biology Probe: Serves as a versatile building block for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in the development of specialty chemicals and advanced organic materials with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	7-Amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile
CAS No.	890091-74-4
Molecular Formula	C7H3F3N6
Molecular Weight	228.13 g/mol
Synonyms	7-Amino-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile; 2-(Trifluoromethyl)-7-amino-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile; 890091-74-4; 7-Amino-2-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile; 6-Cyano-7-amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.