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4-Chloro-7-(3-Chlorophenyl)-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine CAS NO 890091-44-8


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CAS No.:890091-44-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloro-7-(3-Chlorophenyl)-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-substituted pyrrolopyrimidine derivative, a privileged scaffold in modern medicinal chemistry. This compound serves as a critical synthetic intermediate for the development of novel kinase inhibitors and targeted therapeutic agents. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of advanced bioactive molecules.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of protein kinase inhibitors targeting various oncology and inflammatory pathways.
  • Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
  • Biochemical Tool Compound: Used in vitro to study enzyme kinetics and cellular signaling mechanisms.
  • Fine Chemical Synthesis: Intermediate for creating more complex, functionalized heterocyclic compounds with specialized properties.
  • Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical candidates.

Basic Information

Product Name 4-Chloro-7-(3-Chlorophenyl)-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No. 890091-44-8
Molecular Formula C18H11Cl2N3
Molecular Weight 340.21 g/mol
Synonyms 4-Chloro-7-(3-chlorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(3-chlorophenyl)-5-phenyl-; 4-Chloro-7-(3-chlorophenyl)-5-phenylpyrrolo[2,3-d]pyrimidine; 890091-44-8; AKOS010200010; 4-Chloro-7-(3-chlorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(3-chlorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 890091-44-8)
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Quality Control

Our 4-Chloro-7-(3-Chlorophenyl)-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specification data are provided to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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