Description

8-Chloro-2-m-Tolyl-6,7-Dihydro-5H-Cyclopenta[D]-Pyrazolo[1,5-A]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyrimidine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, serving as a sophisticated building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug leads.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds to study specific biological pathways and protein functions.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	8-Chloro-2-m-Tolyl-6,7-Dihydro-5H-Cyclopenta[D]-Pyrazolo[1,5-A]Pyrimidine
CAS No.	889939-52-0
Molecular Formula	C17H14ClN3
Molecular Weight	295.77 g/mol
Synonyms	8-Chloro-2-(3-methylphenyl)-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine; 8-Chloro-2-(m-tolyl)-5,6,7,8-tetrahydrocyclopenta[d]pyrazolo[1,5-a]pyrimidine; 889939-52-0; Cyclopenta[d]pyrazolo[1,5-a]pyrimidine, 8-chloro-6,7-dihydro-2-(3-methylphenyl)-5H-; 8-Chloro-2-(3-methylphenyl)-5,6,7,8-tetrahydrocyclopenta[d]pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-m-Tolyl-6,7-Dihydro-5H-Cyclopenta[D]-Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.