Description

7-Chloro-2-(3-Methoxy-Phenyl)-5-Phenyl-Pyrazolo[1,5-A]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitors and targeted cancer therapies.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening.
• Academic & Contract Research: Employed in university and CRO laboratories for investigating new biological pathways and mechanisms of action.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	7-Chloro-2-(3-Methoxy-Phenyl)-5-Phenyl-Pyrazolo[1,5-A]Pyrimidine
CAS No.	889939-49-5
Molecular Formula	C19H14ClN3O
Molecular Weight	335.79 g/mol
Synonyms	7-Chloro-2-(3-methoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine; 7-Chloro-2-(3-methoxyphenyl)-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 7-chloro-2-(3-methoxyphenyl)-5-phenyl-; 889939-49-5; 7-Chloro-2-(3-methoxy-phenyl)-5-phenyl-pyrazolo[1,5-a]pyrimidine; 5-Phenyl-7-chloro-2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(3-Methoxy-Phenyl)-5-Phenyl-Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.