Description

(R)-2-Chloro-7-Ethyl-8-Isopropyl-7,8-Dihydropteridin-6(5H)-One is a high-purity, chiral pteridinone derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or a potential pharmacophore for designing novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors, particularly for projects involving kinase inhibition, targeted cancer therapies, and other specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel small-molecule drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold or precursor for the development of selective kinase inhibitors.
• Oncology Drug Discovery: Investigated for its potential in creating targeted therapies for various cancer types.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Chemistry: Employed in route scouting and scale-up optimization for active pharmaceutical ingredient (API) manufacturing.
• Biochemical Tool Compound: May be used in vitro to study specific enzymatic pathways and biological mechanisms.

Basic Information

Product Name	(R)-2-Chloro-7-Ethyl-8-Isopropyl-7,8-Dihydropteridin-6(5H)-One
CAS No.	889877-77-4
Molecular Formula	C11H16ClN3O
Molecular Weight	241.72 g/mol
Synonyms	(R)-2-Chloro-7-ethyl-8-(propan-2-yl)-5,6,7,8-tetrahydropteridin-6-one; (6R)-2-Chloro-7-ethyl-8-isopropyl-7,8-dihydro-5H-pteridin-6-one; 889877-77-4; (R)-enantiomer of 2-chloro-7-ethyl-8-isopropyl-7,8-dihydropteridin-6(5H)-one; Chiral pteridinone derivative
EINECS	Contact for details

Quality Control

Our (R)-2-Chloro-7-Ethyl-8-Isopropyl-7,8-Dihydropteridin-6(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.