Description

4-Pyrimidinecarboxylic Acid, 1,6-Dihydro-5-Hydroxy-1-Methyl-2-[1-Methyl-1-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]-6-Oxo-, Methyl Ester is a complex, high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its unique pyrimidine core structure enables the creation of molecules with specific biological activities. Pharmaceutical research and development organizations, as well as specialty chemical manufacturers, need this material for constructing sophisticated molecular architectures in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Organic Synthesis Reagent: Used in complex multi-step syntheses to introduce functionalized pyrimidine moieties into target molecules.
• Research & Development: Essential for medicinal chemistry programs exploring structure-activity relationships (SAR) in academic and industrial labs.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Fine Chemical Production: Acts as a precursor for manufacturing specialized, high-value chemicals used in various advanced applications.

Basic Information

Product Name	4-Pyrimidinecarboxylic Acid, 1,6-Dihydro-5-Hydroxy-1-Methyl-2-[1-Methyl-1-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]-6-Oxo-, Methyl Ester
CAS No.	888504-27-6
Molecular Formula	C19H23N3O6
Molecular Weight	389.40 g/mol
Synonyms	Methyl 5-hydroxy-1-methyl-2-[1-methyl-1-[(phenylmethoxy)carbonylamino]ethyl]-6-oxo-1,6-dihydropyrimidine-4-carboxylate; 1,6-Dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]-6-oxo-, methyl ester; CBZ-protected pyrimidine ester intermediate; N-Carbobenzyloxy pyrimidine derivative.
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinecarboxylic Acid derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.