Description

5-(2,3-Difluorophenyl)Nicotinaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its difluorophenyl and nicotinaldehyde functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the difluorophenyl moiety.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalytic and material science applications.
• Fluorinated Compound Library: An essential component for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	5-(2,3-Difluorophenyl)Nicotinaldehyde
CAS No.	887973-80-0
Molecular Formula	C12H7F2NO
Molecular Weight	219.19 g/mol
Synonyms	5-(2,3-Difluorophenyl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 5-(2,3-difluorophenyl)-; Nicotinaldehyde, 5-(2,3-difluorophenyl)-; 5-(2,3-Difluorophenyl)-3-pyridylcarboxaldehyde; 5-(2,3-Difluorophenyl)-3-formylpyridine
EINECS	Contact for details

Quality Control

Our 5-(2,3-Difluorophenyl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.