Description

Methyl 4-(Trifluoromethyl)Pyrimidine-2-Carboxylate is a high-value fluorinated pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioactivity.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and functional materials.
• Organic Synthesis & Catalysis: A versatile reagent for constructing complex heterocyclic scaffolds in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	Methyl 4-(Trifluoromethyl)Pyrimidine-2-Carboxylate
CAS No.	887626-20-2
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	Methyl 4-(trifluoromethyl)pyrimidine-2-carboxylate; 2-Pyrimidinecarboxylic acid, 4-(trifluoromethyl)-, methyl ester; Methyl 4-trifluoromethylpyrimidine-2-carboxylate; 4-(Trifluoromethyl)pyrimidine-2-carboxylic acid methyl ester; 887626-20-2
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(Trifluoromethyl)Pyrimidine-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong alkalis and sources of fluoride ions. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.