Description

4,8-Dichloro-2-Trifluoromethyl-Quinazoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both halogen and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinazoline core.
• Material Science Research: Acts as a building block for creating specialty polymers, liquid crystals, or organic electronic materials due to its electron-deficient character.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4,8-Dichloro-2-Trifluoromethyl-Quinazoline
CAS No.	887592-26-9
Molecular Formula	C9H3Cl2F3N2
Molecular Weight	267.04 g/mol
Synonyms	2-Trifluoromethyl-4,8-dichloroquinazoline; 4,8-Dichloro-2-(trifluoromethyl)quinazoline; Quinazoline, 4,8-dichloro-2-(trifluoromethyl)-; 887592-26-9; 4,8-Dichloro-2-trifluoromethylquinazoline
EINECS	Contact for details

Quality Control

Every batch of 4,8-Dichloro-2-Trifluoromethyl-Quinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.