Description

4,8-Dichloro-2-tert-Butyl-Quinazoline is a high-value, multi-functional quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other therapeutic pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysis, or specialty polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom synthesis projects and scale-up manufacturing under cGMP or ISO standards.

Basic Information

Product Name	4,8-Dichloro-2-tert-Butyl-Quinazoline
CAS No.	887592-17-8
Molecular Formula	C₁₂H₁₂Cl₂N₂
Molecular Weight	255.14 g/mol
Synonyms	2-(tert-Butyl)-4,8-dichloroquinazoline; 4,8-Dichloro-2-(1,1-dimethylethyl)quinazoline; 4,8-Dichloro-2-tert-butylquinazoline; 2-tert-Butyl-4,8-dichloroquinazoline; Quinazoline, 4,8-dichloro-2-(1,1-dimethylethyl)-; 4,8-Dichloro-2-(tert-butyl)quinazoline
EINECS	Contact for details

Quality Control

Our 4,8-Dichloro-2-tert-Butyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.