Description

2-Phenyl-5-(Pyrimidin-4-Yl)-4-(6-(Trifluoromethyl)Pyridin-3-Yl)Pyrimidine is a high-value, multi-heterocyclic organic compound featuring a trifluoromethylpyridine moiety, which is critical for modulating biological activity and physicochemical properties. This compound is primarily utilized as a sophisticated pharmaceutical intermediate in the research and development of novel therapeutic agents. It is essential for medicinal chemistry researchers and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology and inflammatory disease research.
• Kinase Inhibitor Development: Core scaffold for the design and synthesis of novel protein kinase inhibitors due to its privileged pyrimidine-pyridine structure.
• Agrochemical Research: Intermediate in the development of advanced crop protection agents and pesticides.
• Material Science: Potential precursor for organic electronic materials and ligands in catalytic systems.
• Chemical Biology: Used as a molecular probe or tool compound for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	2-Phenyl-5-(Pyrimidin-4-Yl)-4-(6-(Trifluoromethyl)Pyridin-3-Yl)Pyrimidine
CAS No.	887423-31-6
Molecular Formula	C26H16F3N5
Molecular Weight	455.44 g/mol
Synonyms	4-(6-(Trifluoromethyl)-3-pyridinyl)-2-phenyl-5-(4-pyrimidinyl)pyrimidine; 2-Phenyl-5-(4-pyrimidinyl)-4-[6-(trifluoromethyl)-3-pyridinyl]pyrimidine; 4-[6-(Trifluoromethyl)pyridin-3-yl]-2-phenyl-5-(pyrimidin-4-yl)pyrimidine; 887423-31-6; UNII-2H4F8V8F8U; 2-Phenyl-5-(pyrimidin-4-yl)-4-(6-(trifluoromethyl)pyridin-3-yl)pyrimidine; 4-(6-(Trifluoromethyl)pyridin-3-yl)-2-phenyl-5-(pyrimidin-4-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Phenyl-5-(Pyrimidin-4-Yl)-4-(6-(Trifluoromethyl)Pyridin-3-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.