Description

4-(4-Chlorophenyl)-5-(Methylsulphonyl)-2-[6-(Trifluoromethyl)Pyridin-3-Yl]Pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a unique trifluoromethylpyridine-pyrimidine scaffold that is highly sought after for its potential biological activity. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging the bioactivity of the pyrimidine and trifluoromethylpyridine motifs.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: An important precursor for creating complex, multi-functional molecules in custom synthesis and contract manufacturing.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study specific enzyme or receptor pathways.

Basic Information

Product Name	4-(4-Chlorophenyl)-5-(Methylsulphonyl)-2-[6-(Trifluoromethyl)Pyridin-3-Yl]Pyrimidine
CAS No.	887418-36-2
Molecular Formula	C17H11ClF3N3O2S
Molecular Weight	413.80 g/mol
Synonyms	4-(4-Chlorophenyl)-5-(methylsulfonyl)-2-[6-(trifluoromethyl)pyridin-3-yl]pyrimidine; 2-[6-(Trifluoromethyl)-3-pyridinyl]-5-(methylsulfonyl)-4-(4-chlorophenyl)pyrimidine; 4-(4-Chlorophenyl)-5-methylsulfonyl-2-(6-trifluoromethylpyridin-3-yl)pyrimidine; CAS 887418-36-2
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-5-(Methylsulphonyl)-2-[6-(Trifluoromethyl)Pyridin-3-Yl]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.