Description

Methyl-2-Methoxy-4-Trifluoromethyl Pyrimidine-5-Carboxylate is a high-value fluorinated pyrimidine derivative, a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethyl group and a carboxylate ester, makes it an essential intermediate for creating compounds with enhanced biological activity and metabolic stability. This product is primarily required by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or intermediate in the development of specialty polymers and advanced materials with specific fluorinated properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic frameworks and exploring structure-activity relationships (SAR).
• Ligand and Catalyst Development: Used in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its modifiable functional groups.

Basic Information

Item	Details
Product Name	Methyl-2-Methoxy-4-Trifluoromethyl Pyrimidine-5-Carboxylate
CAS No.	887408-51-7
Molecular Formula	C9H7F3N2O3
Molecular Weight	248.16 g/mol
Synonyms	Methyl 2-methoxy-4-(trifluoromethyl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-methoxy-4-(trifluoromethyl)-, methyl ester; 2-Methoxy-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester; Methyl 2-methoxy-4-trifluoromethyl-5-pyrimidinecarboxylate; 887408-51-7; Methyl 2-methoxy-4-(trifluoromethyl)-5-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl-2-Methoxy-4-Trifluoromethyl Pyrimidine-5-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and agrochemical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.