Description

3-(6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinyl)-3-Oxopropanenitrile is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and cyanoacetamide functionalities, makes it a versatile precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and CNS-active therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine core.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic frameworks and fine chemicals for material science and catalysis.
• Bioconjugation & Probe Development: The reactive cyano and amino groups facilitate its use in creating labeled compounds and molecular probes for biochemical research.
• Academic & Institutional R&D: Serves as a valuable reagent for methodological studies and the discovery of new chemical reactions in university and corporate laboratories.

Basic Information

Product Name	3-(6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinyl)-3-Oxopropanenitrile
CAS No.	887352-46-7
Molecular Formula	C9H10N4O3
Molecular Weight	222.20 g/mol
Synonyms	3-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-3-oxopropanenitrile; 2-Cyano-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)acetamide; 6-Amino-1,3-dimethyl-5-(2-cyanoacetyl)pyrimidine-2,4(1H,3H)-dione; 5-(2-Cyanoacetyl)-6-amino-1,3-dimethyluracil; 6-Amino-1,3-dimethyl-5-(cyanomethylcarbonyl)uracil; 5-(Cyanomethylcarbonyl)-6-amino-1,3-dimethyluracil; 3-Oxo-3-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-ylamino)propanenitrile
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Quality Control

Our 3-(6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinyl)-3-Oxopropanenitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.