Description

2-[3,5-Bis(Trifluoromethyl)Phenoxy]Ethanol is a specialized fluorinated aromatic ether-alcohol building block. This compound is valued for its unique combination of a polar hydroxyl group and a highly lipophilic, electron-deficient trifluoromethyl-substituted aromatic ring, making it a critical intermediate in advanced synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring enhanced metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting materials, improving charge transport and stability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to impart hydrophobicity, chemical resistance, and low surface energy to specialty polymers and coatings.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for catalysis, leveraging the electron-withdrawing aromatic system.
• Advanced Material Research: Employed in academic and industrial R&D for exploring new fluorinated compounds with unique optical or electronic properties.

Basic Information

Product Name	2-[3,5-Bis(Trifluoromethyl)Phenoxy]Ethanol
CAS No.	887268-12-4
Molecular Formula	C10H6F6O2
Molecular Weight	272.14 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenoxy]ethan-1-ol; Ethanol, 2-[3,5-bis(trifluoromethyl)phenoxy]-; 3,5-Bis(trifluoromethyl)phenoxyethanol; 2-(3,5-Bis(trifluoromethyl)phenoxy)ethanol; α-(3,5-Bis(trifluoromethyl)phenoxy)ethanol; 1-Hydroxy-2-[3,5-bis(trifluoromethyl)phenoxy]ethane; 3,5-Bis(trifluoromethyl)phenyl 2-hydroxyethyl ether
EINECS	Contact for details

Quality Control

Our 2-[3,5-Bis(Trifluoromethyl)Phenoxy]Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.