Description

2-Fluoro-6-Nitrobenzenesulphonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a versatile sulfonylation reagent, enabling the introduction of the 2-fluoro-6-nitrobenzenesulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides with specific sulfonylurea or sulfonamide activity.
• Peptide Chemistry: Acts as a protecting group reagent (e.g., a Nosyl chloride analog) for amines in peptide synthesis.
• Material Science Research: Employed in the creation of specialty polymers and functional materials that incorporate sulfonyl groups.
• Chemical Biology Probes: Useful for labeling proteins or other biomolecules to study biological pathways and interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring fluorinated nitroaromatic sulfonyl derivatives.

Basic Information

Product Name	2-Fluoro-6-Nitrobenzenesulphonyl Chloride
CAS No.	887266-98-0
Molecular Formula	C6H3ClFNO4S
Molecular Weight	239.61 g/mol
Synonyms	2-Fluoro-6-nitrobenzenesulfonyl chloride; 1-Fluoro-2-nitro-6-(chlorosulfonyl)benzene; 2-Nitro-6-fluorobenzenesulfonyl chloride; 6-Fluoro-2-nitrobenzenesulfonyl chloride; 2-Fluoro-6-nitrobenzene-1-sulfonyl chloride; NSC 405124; Benzenesulfonyl chloride, 2-fluoro-6-nitro-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Nitrobenzenesulphonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.