Description

4-Fluoro-3-Methoxybenzenesulphonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where the sulfonamide group contributes to biological activity.
• Chemical Research & Development: Serves as a versatile reagent for introducing the sulfonyl chloride group in medicinal chemistry and process optimization studies.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke fine chemicals.

Basic Information

Product Name	4-Fluoro-3-Methoxybenzenesulphonyl Chloride
CAS No.	887266-97-9
Molecular Formula	C7H6ClFO3S
Molecular Weight	224.64 g/mol
Synonyms	4-Fluoro-3-methoxybenzenesulfonyl chloride; 3-Methoxy-4-fluorobenzenesulfonyl chloride; 1-Fluoro-2-methoxy-4-(chlorosulfonyl)benzene; 4-Fluoro-3-methoxybenzene-1-sulfonyl chloride; 887266-97-9; 4-Fluoro-3-methoxy phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methoxybenzenesulphonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.