Description

5-([(4,6-Dimethylpyrimidin-2-Yl)Thio]Methyl)-4-(4-Fluorophenyl)-4H-1,2,4-Triazole-3-Thiol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is essential for research and development chemists and pharmaceutical manufacturers engaged in creating next-generation medications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and antifungal research.
• Agrochemical Research: Serves as a core structure for developing new pesticides and fungicides due to its triazole and pyrimidine motifs.
• Chemical Biology Probe: Used in biochemical research to study enzyme inhibition and protein-ligand interactions.
• Material Science: Potential building block for specialized polymers or ligands in catalytic systems.
• Academic & Industrial R&D: Fundamental compound for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-([(4,6-Dimethylpyrimidin-2-Yl)Thio]Methyl)-4-(4-Fluorophenyl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	887205-52-9
Molecular Formula	C15H14FN5S2
Molecular Weight	347.43 g/mol
Synonyms	4-(4-Fluorophenyl)-5-[(4,6-dimethyl-2-pyrimidinyl)thio]methyl]-4H-1,2,4-triazole-3-thiol; 5-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol; 4-(4-Fluorophenyl)-5-(((4,6-dimethylpyrimidin-2-yl)thio)methyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; CAS 887205-52-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.