Description

4-Chloro-5-Phenyl-7-[3-(Trifluoromethyl)Phenyl]-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is of significant commercial importance due to its role as a critical building block in the synthesis of novel, biologically active molecules, particularly kinase inhibitors. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of targeted therapies for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially protein kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Biochemical Tool Compound: Serves as a reference standard or a core scaffold for developing biochemical probes to study enzyme function and cellular pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-5-Phenyl-7-[3-(Trifluoromethyl)Phenyl]-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	887202-35-9
Molecular Formula	C19H11ClF3N3
Molecular Weight	373.76 g/mol
Synonyms	4-Chloro-5-phenyl-7-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-phenyl-7-[3-(trifluoromethyl)phenyl]-; 4-Chloro-5-phenyl-7-(3-trifluoromethylphenyl)-7H-pyrrolo[2,3-d]pyrimidine; CAS 887202-35-9
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Phenyl-7-[3-(Trifluoromethyl)Phenyl]-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.