Description

2,3-Difluoro-4-Methylaniline is a fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the strategically positioned fluorine atoms and the amino group, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity, metabolic stability, and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy, thermal stability, and luminescent properties.
• Polymer & Resin Modifiers: Incorporated into specialty polymers to alter thermal, chemical, and surface properties for high-performance coatings and engineering plastics.
• Dyestuff & Pigment Manufacturing: Acts as a starting material for synthesizing novel, light-fast fluorinated dyes and pigments.
• Cross-Coupling Reactions: A valuable substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions to create complex biaryl amines.

Basic Information

Product Name	2,3-Difluoro-4-Methylaniline
CAS No.	886503-79-3
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	4-Methyl-2,3-difluoroaniline; 2,3-Difluoro-p-toluidine; 2,3-Difluoro-4-methylbenzenamine; 2,3-Difluoro-4-toluidine; Benzenamine, 2,3-difluoro-4-methyl-; 4-Amino-2,3-difluorotoluene
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methylaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature (store under inert atmosphere), it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.