Description

3-Chloro-2,4-Difluorobenzyl Alcohol is a versatile fluorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of halogen and fluorine atoms on the aromatic ring, which allows for precise structural modifications and the introduction of unique physicochemical properties into target molecules. This compound is essential for R&D chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring halogenated benzyl motifs for enhanced bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoro and chloro substituents contribute to product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Functional Polymer Monomer: Employed to introduce fluorinated benzyl groups into polymer chains, modifying properties like chemical resistance, thermal stability, and surface energy.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl and heteroaryl structures.
• Organic Synthesis Building Block: Utilized in various transformations, including etherification, esterification, and oxidation to the corresponding aldehyde or acid.

Basic Information

Item	Details
Product Name	3-Chloro-2,4-Difluorobenzyl Alcohol
CAS No.	886501-09-3
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	(3-Chloro-2,4-difluorophenyl)methanol; 2,4-Difluoro-3-chlorobenzyl Alcohol; 3-Chloro-2,4-difluorobenzenemethanol; 886501-09-3; Benzyl alcohol, 3-chloro-2,4-difluoro-; (3-Chloro-2,4-difluorophenyl)carbinol
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4-Difluorobenzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.