Description

2-Fluoro-4-Pyrrolidin-1-Yl-Benzaldehyde is a high-purity fluorinated aromatic aldehyde derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both a fluorine atom and a pyrrolidine substituent, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly for central nervous system (CNS) and oncology targets, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its structural motifs to create compounds with specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where fluorinated aromatic systems are valuable.
• Chemical Biology Probes: Utilized to build fluorescent tags or molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-Fluoro-4-Pyrrolidin-1-Yl-Benzaldehyde
CAS No.	886500-78-3
Molecular Formula	C11H12FNO
Molecular Weight	193.22 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-2-fluorobenzaldehyde; 2-Fluoro-4-(1-pyrrolidinyl)benzaldehyde; 2-Fluoro-4-pyrrolidin-1-ylbenzaldehyde; 886500-78-3; Benzaldehyde, 2-fluoro-4-(1-pyrrolidinyl)-; 2-Fluoro-4-(pyrrolidin-1-yl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Pyrrolidin-1-Yl-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.