Description

(7-Chloro-3-Ethyl-4-Oxo-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid CAS NO 886500-56-7 is a high-purity, advanced pharmaceutical intermediate characterized by its quinazolinone core structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• Active Pharmaceutical Ingredient (API) Development: Employed in the construction of complex molecular architectures for new APIs.
• Biochemical Reagent: Utilized in biochemical assays and as a tool compound for probing enzyme interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.
• Academic Research: Used in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	(7-Chloro-3-Ethyl-4-Oxo-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid
CAS No.	886500-56-7
Molecular Formula	C₁₂H₁₁ClN₂O₃S
Molecular Weight	298.74 g/mol
Synonyms	2-[(7-Chloro-3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio]acetic acid; (7-Chloro-3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanylacetic acid; 2-((7-Chloro-3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetic acid; Quinazolin-2-ylthioacetic acid derivative; CAS 886500-56-7; 7-Chloro-3-ethyl-2-mercapto-4(3H)-quinazolinone acetic acid derivative; 2-(7-Chloro-3-ethyl-4-oxoquinazolin-2-ylthio)acetic acid
EINECS	Contact for details

Quality Control

Our (7-Chloro-3-Ethyl-4-Oxo-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key specifications such as assay, related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.